Publications

A selected list of recent publications. For more publications, see individual HARC Center members' websites.

D'Orso, I., Grunwell, J.R., Nakamura, R., Das, C. and Frankel, A.D. (2008) Targeting Tat inihibitors in the assembly of HIV-1 transcription complexes. J. Virol. Jul 30 (Epub ahead of print).

Farady, C.J., Egea, P.F., Schneider, E.L., Darragh, M.R. and Craik, C.S. (2008) Structure of an Fab-Protease complex reveals a highly specific non-canonical mechanism of inhibition. J. Mol. Biol., Vol. 380, p. 351-360.

D. Blazek and B.M. Peterlin (2008), Tat-SIRT1 Tango. Molecular Cell, Vol. 29, p. 539-540.

R.S. Aguiar and B.M. Peterlin (2008), APOBEC3 proteins and reverse transcription. Virus Res. Vol. 134, p. 74-85.

R.S. Aguiar, N. Lovsin, A. Tanuri and B.M. Peterlin (2007), Vpr.A3A Chimera inhibits HIV Replication. J. Biol. Chem., Vol. 283, p. 2518-2525.

S.A. Dames, A. Schonichen, A. Svhulte, M. Barboric, B.M. Peterlin, S. Grzesiek and M. Geyer (2007), Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb. PNAS, 104, p. 14312-17

Barboric, M. Yik, J.. Czudnochowski, M., Yang, Z, Chen, R., Contreras, X., Geyer, M., Peterlin, B.M. and Zhou, Q. (2007) Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. Nucleic Acids Res. 35: 2003-2012.

Contreras, X., Barboric, M., Lenassi, T. and Peterlin, B.M. (2007). HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription. PLoS Pathog 3: 1459-1469.