Matija Peterlin, MD

About

Matija Peterlin has studied HIV proteins from structural and functional perspectives for more than two decades. The Peterlin lab uses molecular biology, immunology, virology and genetics to study intractable immunodeficiencies, and has characterized the functions and interactions of several regulatory and accessory proteins, including Tat, Vif and Nef. Dr. Peterlin is co-leader of the Nef project.

Lab website

Publications

  1. Blazek D, Teque F, Mackewicz C, Peterlin M, Levy JA. The CD8+ cell non-cytotoxic antiviral response affects RNA polymerase II-mediated human immunodeficiency virus transcription in infected CD4+ cells. J Gen Virol. 2016 Jan; 97(1):220-4.
  2. Eifler TT, Shao W, Bartholomeeusen K, Fujinaga K, Jäger S, Johnson JR, Luo Z, Krogan NJ, Peterlin BM. Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts. Mol Cell Biol. 2015 Jan; 35(2):468-78.
  3. Peterlin BM, Brogie JE, Price DH. 7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription. Wiley Interdiscip Rev RNA. 2012 Jan-Feb; 3(1):92-103.
  4. Peterlin BM. Transcription elongation takes central stage: the P-TEFb connection. Cell Cycle. 2010 Aug 01; 9(15):2933-4.
  5. Peterlin BM, Price DH. Controlling the elongation phase of transcription with P-TEFb. Mol Cell. 2006 Aug 04; 23(3):297-305.