Professor ph: 1 415 476-8146 fx: 1 415 502-4690 600 16th St, Rm S512C UCSF Box 2280 San Francisco, CA 94158 United States |
Charles Craik studies protease structure and mechanism, including those of HIV, SIV and KSHV, using genetic, biochemical and biophysical methods. The Craik lab applies this knowledge toward drug design and has pioneered new combinatorial technologies to probe protein-protein interaction interfaces and identify inhibitors, as well as developing an array of new expression methods, including those for antibody reagents. Dr. Craik co-leads the HARC project on Vif in vitro studies as well as heading up the Fab Core.